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Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular may be the fact that by right now there are not any long term prescription weightloss pills that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure and heartrate, and mustn't be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug. 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