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We could possibly get through most situations as long as we can preserve the lives from the ones we love. Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err assisting caution and permit the FDA do its job and demand some study be done in order that the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to earn money and that they would say anything to keep people on their medications. Researchers discovered that participants taking this drug for the year, lost weight within four weeks and have kept the load off through the entire 56 weeks with the study. Contrave can be a combination from the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, that might make them far better and safer. Combo-pilling will be the newest fad or also the newest to come under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is now popular may be the fact that as of right now there aren't long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and must not be taken in people who have seizure disorders. The drug may also raise hypertension and heartrate, and must not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. Approving a drug with this many potentially lethal negative effects is inconsistent while using mission statement with the FDA. The power of the drug manufacturing lobby is blatantly evident inside the approval of countless drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety inside US.